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BIIE0246, a potent and highly selective non-peptide neuropeptide Y Y(2) receptor antagonist
1. BIIE0246, a newly synthesized non-peptide neuropeptide Y (NPY) Y(2) receptor antagonist, was able to compete with high affinity (8 to 15 nM) for specific [(125)I]PYY(3–36) binding sites in HEK293 cells transfected with the rat Y(2) receptor cDNA, and in rat brain and human frontal cortex membrane...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2000
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571943/ https://ncbi.nlm.nih.gov/pubmed/10725255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703162 |
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