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Agonist- and antagonist-induced sequestration/internalization of neuropeptide Y Y(1) receptors in HEK293 cells

1. Neuropeptide Y Y(1) receptors are known to internalize following the binding of agonists. In the present study, a pseudopeptide Y(1) receptor antagonist, homodimeric Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-Tyr-CONH(2) (GR231118), also induced Y(1) receptor internalization in human embryonic kidney (HEK29...

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Detalhes bibliográficos
Main Authors: Pheng, Leng Hong, Dumont, Yvan, Fournier, Alain, Chabot, Jean-Guy, Beaudet, Alain, Quirion, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573902/
https://ncbi.nlm.nih.gov/pubmed/12812992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705306
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