JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/β-catenin/CCND1 signaling

Leukemia-initiating cells (LICs) are responsible for the initiation, development, and relapse of leukemia. The identification of novel therapeutic LIC targets is critical to curing leukemia. In this report, we reveal that junctional adhesion molecule 3 (JAM3) is highly enriched in both mouse and hum...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Zhang, Yaping, Xia, Fangzhen, Liu, Xiaoye, Yu, Zhuo, Xie, Li, Liu, Ligen, Chen, Chiqi, Jiang, Haishan, Hao, Xiaoxin, He, Xiaoxiao, Zhang, Feifei, Gu, Hao, Zhu, Jun, Bai, Haitao, Zhang, Cheng Cheng, Chen, Guo-Qiang, Zheng, Junke
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919829/
https://ncbi.nlm.nih.gov/pubmed/29584620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93198
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares