ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways

Targeting leukemia-initiating cells (LICs) is the key to eradicating leukemia and preventing its relapse. Recent studies have indicated that metabolic regulation may play a critical role in the maintenance of stemness in LICs, although the detailed mechanisms are poorly understood. Herein, we provid...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zeng, Hongxiang, Gu, Hao, Chen, Chiqi, Li, Minle, Xia, Fangzhen, Xie, Li, Liu, Xiaoye, Zhang, Feifei, Tong, Xuemei, Wang, Jiangbo, Yu, Zhuo, Zheng, Junke
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122394/
https://ncbi.nlm.nih.gov/pubmed/27224916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9520
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