Biodistribution of Neocarzinostatin Conjugated to Chimeric Fab Fragments of the Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Cancer Xenografts

In this study, we conjugated chimeric Fab fragments of the monoclonal antibody (MAb) A7, which reacts with pancreatic cancers, to the antitumor drug neocarzinostatin (chA7Fab‐NCS) and intravenously injected (125)I‐labeled chA7Fab‐NCS into nude mice bearing a human pancreatic cancer xenograft. We com...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Otsuji, Eigo, Yamaguchi, Toshiharu, Yamaoka, Nobuki, Taniguchi, Katsunori, Kato, Makoto, Kotani, Tatsuya, Kitamura, Kazuya, Takahashi, Toshio
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 1994
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919492/
https://ncbi.nlm.nih.gov/pubmed/8014111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02391.x
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