Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) remains a grave threat to world health with emerging drug resistant strains. One prominent feature of Mtb infection is the extensive reprogramming of host tissue at the site of infection. Here we report that inhibition of matrix metalloproteinase (MMP) activity by a...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Xu, Yitian, Wang, Lihua, Zimmerman, Matthew D., Chen, Kai-Yuan, Huang, Lu, Fu, Dah-Jiun, Kaya, Firat, Rakhilin, Nikolai, Nazarova, Evgeniya V., Bu, Pengcheng, Dartois, Veronique, Russell, David G., Shen, Xiling
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919409/
https://ncbi.nlm.nih.gov/pubmed/29698476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006974
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