Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) remains a grave threat to world health with emerging drug resistant strains. One prominent feature of Mtb infection is the extensive reprogramming of host tissue at the site of infection. Here we report that inhibition of matrix metalloproteinase (MMP) activity by a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Xu, Yitian, Wang, Lihua, Zimmerman, Matthew D., Chen, Kai-Yuan, Huang, Lu, Fu, Dah-Jiun, Kaya, Firat, Rakhilin, Nikolai, Nazarova, Evgeniya V., Bu, Pengcheng, Dartois, Veronique, Russell, David G., Shen, Xiling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919409/
https://ncbi.nlm.nih.gov/pubmed/29698476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006974
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