TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies

EBV infection is associated with a number of malignancies of clinical unmet need, including Hodgkin lymphoma, nasopharyngeal carcinoma, gastric cancer, and posttransplant lymphoproliferative disease (PTLD), all of which express the EBV protein latent membrane protein 2A (LMP2A), an antigen that is d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Ahmed, Mahiuddin, Lopez-Albaitero, Andres, Pankov, Dmitry, Santich, Brian H., Liu, Hong, Yan, Su, Xiang, Jingyi, Wang, Pei, Hasan, Aisha N., Selvakumar, Annamalai, O’Reilly, Richard J., Liu, Cheng, Cheung, Nai-Kong V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916246/
https://ncbi.nlm.nih.gov/pubmed/29467338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97805
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg