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High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening
G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins and thus constitute an important family of therapeutic targets. Therefore, significant effort has been put towards the identification of novel ligands that can modulate the activity of a GPCR target with high ef...
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| Wydane w: | Chem Sci |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Royal Society of Chemistry
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5916221/ https://ncbi.nlm.nih.gov/pubmed/29732102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04698g |
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