High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening

G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins and thus constitute an important family of therapeutic targets. Therefore, significant effort has been put towards the identification of novel ligands that can modulate the activity of a GPCR target with high ef...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Qin, Shanshan, Meng, Mengmeng, Yang, Dehua, Bai, Wenwen, Lu, Yan, Peng, Yao, Song, Gaojie, Wu, Yiran, Zhou, Qingtong, Zhao, Suwen, Huang, Xiping, McCorvy, John D., Cai, Xiaoqing, Dai, Antao, Roth, Bryan L., Hanson, Michael A., Liu, Zhi-Jie, Wang, Ming-Wei, Stevens, Raymond C., Shui, Wenqing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2018
Aiheet:
Chemistry
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916221/
https://ncbi.nlm.nih.gov/pubmed/29732102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04698g
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