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New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry

The post-translational modifications (PTMs) occurring on microtubules have been implicated in the regulation of microtubule properties and functions. Acetylated K40 of α-tubulin, a hallmark of long-lived stable microtubules, is known to be negatively controlled by histone deacetylase 6 (HDAC6). Howe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Ningning, Xiong, Yun, Li, Shanshan, Ren, Yiran, He, Qianqian, Gao, Siqi, Zhou, Jun, Shui, Wenqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652237/
https://ncbi.nlm.nih.gov/pubmed/26581825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16869
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