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Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
Cilia play important roles in sensing extracellular signals and directing fluid flow. Ciliary dysfunction is associated with a variety of diseases known as ciliopathies. Histone deacetylase 6 (HDAC6) has recently emerged as a major driver of ciliary disassembly, but little is known about the downstr...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526867/ https://ncbi.nlm.nih.gov/pubmed/26246421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12917 |
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