Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

Histone deacetylases (HDACs) deacetylate histones and non-histone proteins, thereby affecting protein activity and gene expression. The regulation and function of the cytoplasmic class IIb HDAC6 in endothelial cells (ECs) is largely unexplored. Here, we demonstrate that HDAC6 is upregulated by hypox...

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Detalhes bibliográficos
Main Authors: Kaluza, David, Kroll, Jens, Gesierich, Sabine, Yao, Tso-Pang, Boon, Reinier A, Hergenreider, Eduard, Tjwa, Marc, Rössig, Lothar, Seto, Edward, Augustin, Hellmut G, Zeiher, Andreas M, Dimmeler, Stefanie, Urbich, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199386/
https://ncbi.nlm.nih.gov/pubmed/21847094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.298
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