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Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6

BACKGROUND: Histone deacetylases (HDACs) are involved in epigenetic gene regulation via deacetylation of acetylated lysine residues of both histone and non-histone proteins. Among the 18 HDACs identified in humans, HDAC8, a class I HDAC, is best understood structurally and enzymatically. However, it...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Vanaja, G. R., Ramulu, Hemalatha Golaconda, Kalle, Arunasree M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930436/
https://ncbi.nlm.nih.gov/pubmed/29716651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0231-4
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