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Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I
Macroautophagy is a conserved eukaryotic process for degradation of cellular components in response to lack of nutrients. It is involved in the development of diseases, notably cancer and neurological disorders including Parkinson's disease. Small molecule autophagy modulators have proven to be...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5916016/ https://ncbi.nlm.nih.gov/pubmed/29732085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05040b |
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