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Mitochondrial uncoupler exerts a synthetic lethal effect against β‐catenin mutant tumor cells
The wingless/int‐1 (Wnt) signal transduction pathway plays a central role in cell proliferation, survival, differentiation and apoptosis. When β‐catenin: a component of the Wnt pathway, is mutated into an active form, cell growth signaling is hyperactive and drives oncogenesis. As β‐catenin is mutat...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406605/ https://ncbi.nlm.nih.gov/pubmed/28107588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13172 |
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