Mycobacterium tuberculosis-Infected Hematopoietic Stem and Progenitor Cells Unable to Express Inducible Nitric Oxide Synthase Propagate Tuberculosis in Mice

Persistence of Mycobacterium tuberculosis within human bone marrow stem cells has been identified as a potential bacterial niche during latent tuberculosis. Using a murine model of tuberculosis, we show here that bone marrow stem and progenitor cells containing M. tuberculosis propagated tuberculosi...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Reece, Stephen T, Vogelzang, Alexis, Tornack, Julia, Bauer, Wolfgang, Zedler, Ulrike, Schommer-Leitner, Sandra, Stingl, Georg, Melchers, Fritz, Kaufmann, Stefan H E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913604/
https://ncbi.nlm.nih.gov/pubmed/29471332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy041
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