Mycobacterium tuberculosis-Infected Hematopoietic Stem and Progenitor Cells Unable to Express Inducible Nitric Oxide Synthase Propagate Tuberculosis in Mice

Persistence of Mycobacterium tuberculosis within human bone marrow stem cells has been identified as a potential bacterial niche during latent tuberculosis. Using a murine model of tuberculosis, we show here that bone marrow stem and progenitor cells containing M. tuberculosis propagated tuberculosi...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Reece, Stephen T, Vogelzang, Alexis, Tornack, Julia, Bauer, Wolfgang, Zedler, Ulrike, Schommer-Leitner, Sandra, Stingl, Georg, Melchers, Fritz, Kaufmann, Stefan H E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913604/
https://ncbi.nlm.nih.gov/pubmed/29471332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy041
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