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Mycobacterium tuberculosis-Infected Hematopoietic Stem and Progenitor Cells Unable to Express Inducible Nitric Oxide Synthase Propagate Tuberculosis in Mice

Persistence of Mycobacterium tuberculosis within human bone marrow stem cells has been identified as a potential bacterial niche during latent tuberculosis. Using a murine model of tuberculosis, we show here that bone marrow stem and progenitor cells containing M. tuberculosis propagated tuberculosi...

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Библиографические подробности
Опубликовано в: :J Infect Dis
Главные авторы: Reece, Stephen T, Vogelzang, Alexis, Tornack, Julia, Bauer, Wolfgang, Zedler, Ulrike, Schommer-Leitner, Sandra, Stingl, Georg, Melchers, Fritz, Kaufmann, Stefan H E
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913604/
https://ncbi.nlm.nih.gov/pubmed/29471332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy041
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