Neonatal Fc Receptor Regulation of Lung Immunoglobulin and CD103(+) Dendritic Cells Confers Transient Susceptibility to Tuberculosis

The neonatal Fc receptor (FcRn) extends the systemic half-life of IgG antibodies by chaperoning bound Fc away from lysosomal degradation inside stromal and hematopoietic cells. FcRn also transports IgG across mucosal barriers into the lumen, and yet little is known about how FcRn modulates immunity...

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Vogelzang, Alexis, Lozza, Laura, Reece, Stephen T., Perdomo, Carolina, Zedler, Ulrike, Hahnke, Karin, Oberbeck-Mueller, Dagmar, Dorhoi, Anca, Kaufmann, Stefan H. E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038074/
https://ncbi.nlm.nih.gov/pubmed/27481246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00533-16
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