Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB), yet its moderate efficacy against pulmonary TB calls for improved vaccination strategies. Mucosal BCG vaccination generates superior protection against TB in animal models; however, the mechanis...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Perdomo, Carolina, Zedler, Ulrike, Kühl, Anja A., Lozza, Laura, Saikali, Philippe, Sander, Leif E., Vogelzang, Alexis, Kaufmann, Stefan H. E., Kupz, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120139/
https://ncbi.nlm.nih.gov/pubmed/27879332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01686-16
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