Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB), yet its moderate efficacy against pulmonary TB calls for improved vaccination strategies. Mucosal BCG vaccination generates superior protection against TB in animal models; however, the mechanis...

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Bibliographic Details
Published in:mBio
Main Authors: Perdomo, Carolina, Zedler, Ulrike, Kühl, Anja A., Lozza, Laura, Saikali, Philippe, Sander, Leif E., Vogelzang, Alexis, Kaufmann, Stefan H. E., Kupz, Andreas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120139/
https://ncbi.nlm.nih.gov/pubmed/27879332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01686-16
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