Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

General interest in the biological functions of IFN type I in Mycobacterium tuberculosis (Mtb) infection increased after the recent identification of a distinct IFN gene expression signature in tuberculosis (TB) patients. Here, we demonstrate that TB-susceptible mice lacking the receptor for IFN I (...

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Dettagli Bibliografici
Pubblicato in:Eur J Immunol
Autori principali: Dorhoi, Anca, Yeremeev, Vladimir, Nouailles, Geraldine, Weiner, January, Jörg, Sabine, Heinemann, Ellen, Oberbeck-Müller, Dagmar, Knaul, Julia K, Vogelzang, Alexis, Reece, Stephen T, Hahnke, Karin, Mollenkopf, Hans-Joachim, Brinkmann, Volker, Kaufmann, Stefan H E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298793/
https://ncbi.nlm.nih.gov/pubmed/24782112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344219
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