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Concordant and discordant gene expression patterns in mouse strains identify best-fit animal model for human tuberculosis

Immunity in infection, inflammation and malignancy differs markedly in man and mouse. Still, we learn about human immunity in large extent from experimental mouse models. We propose a novel data integration approach which identifies concordant and discordant gene expression patterns of the immune re...

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發表在:Sci Rep
Main Authors: Domaszewska, Teresa, Scheuermann, Lisa, Hahnke, Karin, Mollenkopf, Hans, Dorhoi, Anca, Kaufmann, Stefan H. E., Weiner, January
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608750/
https://ncbi.nlm.nih.gov/pubmed/28935874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11812-x
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