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Concordant and discordant gene expression patterns in mouse strains identify best-fit animal model for human tuberculosis

Immunity in infection, inflammation and malignancy differs markedly in man and mouse. Still, we learn about human immunity in large extent from experimental mouse models. We propose a novel data integration approach which identifies concordant and discordant gene expression patterns of the immune re...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Domaszewska, Teresa, Scheuermann, Lisa, Hahnke, Karin, Mollenkopf, Hans, Dorhoi, Anca, Kaufmann, Stefan H. E., Weiner, January
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608750/
https://ncbi.nlm.nih.gov/pubmed/28935874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11812-x
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