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m(6)A Facilitates eIF4F-Independent mRNA Translation
In eukaryotic cells, protein synthesis typically begins with the binding of eIF4F to the 7-methylguanylate (m(7)G) cap found on the 5’ end of the majority of mRNAs. Surprisingly, overall translational output remains robust under eIF4F inhibition. The broad spectrum of eIF4F-resistant translatomes is...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5913006/ https://ncbi.nlm.nih.gov/pubmed/29107534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.002 |
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