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m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2

Dynamic mRNA modification in the form of N(6)-methyladenosine (m(6)A) adds considerable richness and sophistication to gene regulation. The m(6)A mark is asymmetrically distributed along mature mRNAs, with approximately 35% of m(6)A residues located within the coding region (CDS). It has been sugges...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mao, Yuanhui, Dong, Leiming, Liu, Xiao-Min, Guo, Jiayin, Ma, Honghui, Shen, Bin, Qian, Shu-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877647/
https://ncbi.nlm.nih.gov/pubmed/31767846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13317-9
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