N(6)-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response

The integrated stress response (ISR) facilitates cellular adaptation to stress conditions via the common target eIF2α. During ISR, the selective translation of stress-related mRNAs often relies on alternative mechanisms, such as leaky scanning or reinitiation, but the underlying mechanism remains in...

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Udgivet i:Mol Cell
Main Authors: Zhou, Jun, Wan, Ji, Shu, Xin Erica, Mao, Yuanhui, Liu, Xiao-Min, Yuan, Xin, Zhang, Xingqian, Hess, Martin E., Brüning, Jens C., Qian, Shu-Bing
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816726/
https://ncbi.nlm.nih.gov/pubmed/29429926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.019
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