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Dynamic m(6)A mRNA methylation directs translational control of heat shock response
The most abundant mRNA post-transcriptional modification is N(6)-methyladenosine (m(6)A) that has broad roles in RNA biology(1-5). In mammalian cells, the asymmetric distribution of m(6)A along mRNAs leaves relatively less methylation in the 5′ untranslated region (5′UTR) compared to other regions(6...
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| Vydáno v: | Nature |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4851248/ https://ncbi.nlm.nih.gov/pubmed/26458103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15377 |
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