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Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function
Intestinal epithelial cells form a selectively permeable barrier to protect colon tissues from luminal microbiota and antigens and to mediate nutrient, fluid, and waste flux in the intestinal tract. Dysregulation of the epithelial cell barrier coincides with profound shifts in metabolic energy, espe...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912467/ https://ncbi.nlm.nih.gov/pubmed/29487135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000269 |
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