Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile

por Lanis, Jordi M., Barua, Soumitra, Ballard, Jimmy D.
Publicado em 2010

TcdB from Hypervirulent Clostridium difficile Exhibits Increased Efficiency of Autoprocessing

por Lanis, Jordi M., Hightower, Logan D., Shen, Aimee, Ballard, Jimmy D.
Publicado em 2012

Clostridium difficile 027/BI/NAP1 Encodes a Hypertoxic and Antigenically Variable Form of TcdB

por Lanis, Jordi M., Heinlen, Latisha D., James, Judith A., Ballard, Jimmy D.
Publicado em 2013

Metabolic regulation of intestinal epithelial barrier during inflammation

por Colgan, Sean P, Curtis, Valerie F, Lanis, Jordi M, Glover, Louise E
Publicado no Tissue Barriers (2014)

Tissue metabolism and the inflammatory bowel diseases

por Lanis, Jordi M., Kao, Daniel J., Alexeev, Erica E., Colgan, Sean P.
Publicado no J Mol Med (Berl) (2017)

Exposure of Neutralizing Epitopes in the Carboxyl-terminal Domain of TcdB Is Altered by a Proximal Hypervariable Region

por Larabee, Jason L., Krumholz, Aleze, Hunt, Jonathan J., Lanis, Jordi M., Ballard, Jimmy D.
Publicado no J Biol Chem (2015)

Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function

por Lee, J. Scott, Wang, Ruth X., Alexeev, Erica E., Lanis, Jordi M., Battista, Kayla D., Glover, Louise E., Colgan, Sean P.
Publicado no J Biol Chem (2018)

Memory B Cells Encode Neutralizing Antibody Specific for Toxin B from the Clostridium difficile Strains VPI 10463 and NAP1/BI/027 but with Superior Neutralization of VPI 10463 Toxi...

por Devera, T. Scott, Lang, Gillian A., Lanis, Jordi M., Rampuria, Pragya, Gilmore, Casey L., James, Judith A., Ballard, Jimmy D., Lang, Mark L.
Publicado no Infect Immun (2015)

Microbial-derived Butyrate Promotes Epithelial Barrier Function Through IL-10 Receptor-dependent Repression of Claudin-2

por Zheng, Leon, Kelly, Caleb J., Battista, Kayla D., Schaefer, Rachel, Lanis, Jordi M., Alexeev, Erica E., Wang, Ruth X., Onyiah, Joseph C., Kominsky, Douglas J., Colgan, Sean P.
Publicado no J Immunol (2017)

Tryptophan Metabolite Activation of the Aryl Hydrocarbon Receptor Regulates IL10 Receptor Expression on Intestinal Epithelia

por Lanis, Jordi M., Alexeev, Erica E., Curtis, Valerie F., Kitzenberg, David A., Kao, Daniel J., Battista, Kayla D., Gerich, Mark E., Glover, Louise E., Kominsky, Douglas J., Colgan, Sean P.
Publicado no Mucosal Immunol (2017)

Bile Acids Modulate Colonic MAdCAM-1 Expression in a Murine Model of Combined Cholestasis and Colitis

por Gao, Rachel Y., Shearn, Colin T., Orlicky, David J., Battista, Kayla D., Alexeev, Erica E., Cartwright, Ian M., Lanis, Jordi M., Kostelecky, Rachael E., Ju, Cynthia, Colgan, Sean P., Fennimore, Blair P.
Publicado no Mucosal Immunol (2020)

Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage

por Alexeev, Erica E., Dowdell, Alexander S., Henen, Morkos A., Lanis, Jordi M., Lee, J. Scott, Cartwright, Ian M., Schaefer, Rachel E. M., Ornelas, Alfredo, Onyiah, Joseph C., Vögeli, Beat, Colgan, Sean P.
Publicado no FASEB J (2021)

Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor

por Alexeev, Erica E., Lanis, Jordi M., Kao, Daniel J., Campbell, Eric L., Kelly, Caleb J., Battista, Kayla D., Gerich, Mark E., Jenkins, Brittany R., Walk, Seth T., Kominsky, Douglas J., Colgan, Sean P.
Publicado no Am J Pathol (2018)

Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling

por Curtis, Valerie F., Cartwright, Ian M., Lee, J. Scott, Wang, Ruth X., Kao, Daniel J., Lanis, Jordi M., Burney, Krista M., Welch, Nichole, Hall, Caroline H. T., Goldberg, Matthew S., Campbell, Eric L., Colgan, Sean P.
Publicado no Mol Biol Cell (2018)

Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation

por Cartwright, Ian M., Dowdell, Alexander S., Lanis, Jordi M., Brink, Kathryn R., Mu, Andrew, Kostelecky, Rachael E., Schaefer, Rachel E. M., Welch, Nichole, Onyiah, Joseph C., Hall, Caroline H. T., Gerich, Mark E., Tabor, Jeffrey J., Colgan, Sean P.
Publicado no Proc Natl Acad Sci U S A (2021)

Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3

por Cartwright, Ian M., Curtis, Valerie F., Lanis, Jordi M., Alexeev, Erica E., Welch, Nichole, Goldberg, Matthew S., Schaefer, Rachel E.M, Gao, Rachel Y., Chun, Carlene, Fennimore, Blair, Onyiah, Joseph C., Gerich, Mark E., Dempsey, Peter J., Colgan, Sean P.
Publicado no Mucosal Immunol (2019)

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

por Kelly, Caleb J., Zheng, Leon, Campbell, Eric L., Saeedi, Bejan, Scholz, Carsten C., Bayless, Amanda J., Wilson, Kelly E., Glove, Louise E., Kominsky, Douglas J., Magnuson, Aaron, Weir, Tiffany L., Ehrentraut, Stefan F., Pickel, Christina, Kuhn, Kristine A., Lanis, Jordi M., Nguyen, Vu, Taylor, Cormac T., Colgan, Sean P.
Publicado no Cell Host Microbe (2015)