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Tryptophan Metabolite Activation of the Aryl Hydrocarbon Receptor Regulates IL10 Receptor Expression on Intestinal Epithelia

IL10 is a potent anti-inflammatory cytokine that inhibits the production of pro-inflammatory mediators. Signaling by IL10 occurs through the IL10 receptor (IL10R), which is expressed in numerous cell types, including intestinal epithelial cells (IEC), where it is associated with development and main...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Lanis, Jordi M., Alexeev, Erica E., Curtis, Valerie F., Kitzenberg, David A., Kao, Daniel J., Battista, Kayla D., Gerich, Mark E., Glover, Louise E., Kominsky, Douglas J., Colgan, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515702/
https://ncbi.nlm.nih.gov/pubmed/28098246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.133
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