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TcdB from Hypervirulent Clostridium difficile Exhibits Increased Efficiency of Autoprocessing

TcdB, an intracellular bacterial toxin that inactivates small GTPases, is a major Clostridium difficile virulence factor. Recent studies have found that TcdB produced by emerging/hypervirulent strains of C. difficile is more potent than TcdB from historical strains, and in the current work, studies...

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Bibliographic Details
Main Authors: Lanis, Jordi M., Hightower, Logan D., Shen, Aimee, Ballard, Jimmy D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313004/
https://ncbi.nlm.nih.gov/pubmed/22372854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08009.x
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