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The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein

The 16.5 kb mitochondrial genome is subjected to damage from reactive oxygen species (ROS) generated in the cell during normal cellular metabolism and external sources such as ionizing radiation and ultraviolet light. ROS cause harmful damage to DNA bases that could result in mutagenesis and various...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Sharma, Nidhi, Chakravarthy, Srinivas, Longley, Matthew J., Copeland, William C., Prakash, Aishwarya
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911420/
https://ncbi.nlm.nih.gov/pubmed/29522991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.02.012
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