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PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance
BACKGROUND: PBP4 is typically considered unimportant for conferring high-level β-lactam resistance in Staphylococcus aureus. Mutations in PBP4 have been associated with β-lactam non-susceptibility among natural strains of S. aureus. We have previously shown that PBP4 can mediate high-level β-lactam...
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| Publicado no: | J Antimicrob Chemother |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5909641/ https://ncbi.nlm.nih.gov/pubmed/29360990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx531 |
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