High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4)

Penicillin-binding protein 4 (PBP4), a nonessential, low-molecular-weight penicillin-binding protein of Staphylococcus aureus, has been implicated in low-level resistance to β-lactam antibiotics, although the mechanism is unknown. Mutations in PBP4 and its promoter were identified in a laboratory-ge...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Hamilton, Stephanie M., Alexander, J. Andrew N., Choo, Eun Ju, Basuino, Li, da Costa, Thaina M., Severin, Anatoly, Chung, Marilyn, Aedo, Sandra, Strynadka, Natalie C. J., Tomasz, Alexander, Chatterjee, Som S., Chambers, Henry F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444179/
https://ncbi.nlm.nih.gov/pubmed/28373193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02727-16
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