Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) causes serious community-acquired and nosocomial infections worldwide. MRSA strains are resistant to a variety of antibiotics, including the classic penicillin and cephalosporin classes of β-lactams, making them intractable to treatment. Although β-...

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Vydáno v:J Biol Chem
Hlavní autoři: Alexander, J. Andrew N., Chatterjee, Som S., Hamilton, Stephanie M., Eltis, Lindsay D., Chambers, Henry F., Strynadka, Natalie C. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314119/
https://ncbi.nlm.nih.gov/pubmed/30366985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004952
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