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The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation

Cajal bodies (CBs) are nuclear non-membrane bound organelles where small nuclear ribonucleoprotein particles (snRNPs) undergo their final maturation and quality control before they are released to the nucleoplasm. However, the molecular mechanism how immature snRNPs are targeted and retained in CBs...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Roithová, Adriana, Klimešová, Klára, Pánek, Josef, Will, Cindy L, Lührmann, Reinhard, Staněk, David, Girard, Cyrille
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909452/
https://ncbi.nlm.nih.gov/pubmed/29415178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky070
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