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U2 snRNA-Protein Contacts in Purified Human 17S U2 snRNPs and in Spliceosomal A and B Complexes

The 17S U2 snRNP plays an essential role in branch point selection and catalysis during pre-mRNA splicing. Much remains to be learned about the molecular architecture of the U2 snRNP, including which proteins contact the functionally important 5′ end of the U2 snRNA. Here, RNA-protein interactions w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dybkov, Olexandr, Will, Cindy L., Deckert, Jochen, Behzadnia, Nastaran, Hartmuth, Klaus, Lührmann, Reinhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430325/
https://ncbi.nlm.nih.gov/pubmed/16537922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2803-2816.2006
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