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Proximity of conserved U6 and U2 snRNA elements to the 5′ splice site region in activated spliceosomes

Major structural changes occur in the spliceosome during its catalytic activation, which immediately precedes the splicing of pre-mRNA. Whereas changes in snRNA conformation are well documented at the level of secondary RNA–RNA interactions, little is known about the tertiary structure of this RNA–R...

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Detalhes bibliográficos
Main Authors: Rhode, Britta M, Hartmuth, Klaus, Westhof, Eric, Lührmann, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478171/
https://ncbi.nlm.nih.gov/pubmed/16688215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601134
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