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Proximity of conserved U6 and U2 snRNA elements to the 5′ splice site region in activated spliceosomes
Major structural changes occur in the spliceosome during its catalytic activation, which immediately precedes the splicing of pre-mRNA. Whereas changes in snRNA conformation are well documented at the level of secondary RNA–RNA interactions, little is known about the tertiary structure of this RNA–R...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478171/ https://ncbi.nlm.nih.gov/pubmed/16688215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601134 |
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