The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation

Cajal bodies (CBs) are nuclear non-membrane bound organelles where small nuclear ribonucleoprotein particles (snRNPs) undergo their final maturation and quality control before they are released to the nucleoplasm. However, the molecular mechanism how immature snRNPs are targeted and retained in CBs...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Roithová, Adriana, Klimešová, Klára, Pánek, Josef, Will, Cindy L, Lührmann, Reinhard, Staněk, David, Girard, Cyrille
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
RNA and RNA-protein complexes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909452/
https://ncbi.nlm.nih.gov/pubmed/29415178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky070
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