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The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation

Cajal bodies (CBs) are nuclear non-membrane bound organelles where small nuclear ribonucleoprotein particles (snRNPs) undergo their final maturation and quality control before they are released to the nucleoplasm. However, the molecular mechanism how immature snRNPs are targeted and retained in CBs...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Roithová, Adriana, Klimešová, Klára, Pánek, Josef, Will, Cindy L, Lührmann, Reinhard, Staněk, David, Girard, Cyrille
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909452/
https://ncbi.nlm.nih.gov/pubmed/29415178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky070
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