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The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation

Cajal bodies (CBs) are nuclear non-membrane bound organelles where small nuclear ribonucleoprotein particles (snRNPs) undergo their final maturation and quality control before they are released to the nucleoplasm. However, the molecular mechanism how immature snRNPs are targeted and retained in CBs...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Roithová, Adriana, Klimešová, Klára, Pánek, Josef, Will, Cindy L, Lührmann, Reinhard, Staněk, David, Girard, Cyrille
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909452/
https://ncbi.nlm.nih.gov/pubmed/29415178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky070
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