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Histone deacetylase inhibitor-based chromatin precipitation for identification of targeted genomic loci

Histone deacetylase (HDAC) catalyzes the removal of acetyl marks from histones, effectively regulating gene expression. Genome wide chromatin immunoprecipitation (ChIP) studies have shown HDACs are present on numerous active and repressed genes. However, HDAC inhibitors (HDACi) only regulate a small...

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Detalhes bibliográficos
Publicado no:J Biol Methods
Main Authors: Hanigan, Thomas W., Danes, Jeanne M., Taha, Taha Y., Frasor, Jonna, Petukhov, Pavel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Journal of Biological Methods 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909381/
https://ncbi.nlm.nih.gov/pubmed/29682593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14440/jbm.2018.216
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