Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p

BACKGROUND: Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory. The low viability and angiogenic capacity of the implanted cells in the local infarct tissues restrict their further application...

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Библиографические подробности
Опубликовано в: :Stem Cell Res Ther
Главные авторы: Hou, Jingying, Wang, Lingyun, Wu, Quanhua, Zheng, Guanghui, Long, Huibao, Wu, Hao, Zhou, Changqing, Guo, Tianzhu, Zhong, Tingting, Wang, Lei, Chen, Xuxiang, Wang, Tong
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909270/
https://ncbi.nlm.nih.gov/pubmed/29673400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0861-x
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