Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis

BACKGROUND: Cardiac stem cells (CSCs) transplantation has been regarded as an optimal therapeutic approach for cardiovascular disease. However, inferior survival and low differentiation efficiency of these cells in the local infarct site reduce their therapeutic efficacy. In this study, we investiga...

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Gepubliceerd in:Stem Cell Res Ther
Hoofdauteurs: Hou, Jingying, Wang, Lei, Long, Huibao, Wu, Hao, Wu, Quanhua, Zhong, Tingting, Chen, Xuxiang, Zhou, Changqing, Guo, Tianzhu, Wang, Tong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622481/
https://ncbi.nlm.nih.gov/pubmed/28962638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0673-4
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