Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis

BACKGROUND: Cardiac stem cells (CSCs) transplantation has been regarded as an optimal therapeutic approach for cardiovascular disease. However, inferior survival and low differentiation efficiency of these cells in the local infarct site reduce their therapeutic efficacy. In this study, we investiga...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Hou, Jingying, Wang, Lei, Long, Huibao, Wu, Hao, Wu, Quanhua, Zhong, Tingting, Chen, Xuxiang, Zhou, Changqing, Guo, Tianzhu, Wang, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622481/
https://ncbi.nlm.nih.gov/pubmed/28962638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0673-4
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