Hypoxia preconditioning promotes cardiac stem cell survival and cardiogenic differentiation in vitro involving activation of the HIF-1α/apelin/APJ axis

BACKGROUND: Cardiac stem cells (CSCs) transplantation has been regarded as an optimal therapeutic approach for cardiovascular disease. However, inferior survival and low differentiation efficiency of these cells in the local infarct site reduce their therapeutic efficacy. In this study, we investiga...

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Bibliografski detalji
Izdano u:Stem Cell Res Ther
Glavni autori: Hou, Jingying, Wang, Lei, Long, Huibao, Wu, Hao, Wu, Quanhua, Zhong, Tingting, Chen, Xuxiang, Zhou, Changqing, Guo, Tianzhu, Wang, Tong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622481/
https://ncbi.nlm.nih.gov/pubmed/28962638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0673-4
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