Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p

BACKGROUND: Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory. The low viability and angiogenic capacity of the implanted cells in the local infarct tissues restrict their further application...

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Publicado en:Stem Cell Res Ther
Autores principales: Hou, Jingying, Wang, Lingyun, Wu, Quanhua, Zheng, Guanghui, Long, Huibao, Wu, Hao, Zhou, Changqing, Guo, Tianzhu, Zhong, Tingting, Wang, Lei, Chen, Xuxiang, Wang, Tong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909270/
https://ncbi.nlm.nih.gov/pubmed/29673400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0861-x
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