Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p

BACKGROUND: Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory. The low viability and angiogenic capacity of the implanted cells in the local infarct tissues restrict their further application...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Hou, Jingying, Wang, Lingyun, Wu, Quanhua, Zheng, Guanghui, Long, Huibao, Wu, Hao, Zhou, Changqing, Guo, Tianzhu, Zhong, Tingting, Wang, Lei, Chen, Xuxiang, Wang, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909270/
https://ncbi.nlm.nih.gov/pubmed/29673400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0861-x
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