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Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension
OBJECTIVE: The G-protein–coupled receptor APJ and its ligand apelin are highly expressed in the pulmonary vasculature, but their function in this vascular bed is unclear. We hypothesized that disruption of apelin signaling would lead to worsening of the vascular remodeling associated with pulmonary...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113525/ https://ncbi.nlm.nih.gov/pubmed/21233449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.219980 |
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