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Unlocking endosomal entrapment with supercharged arginine-rich peptides

Endosomal entrapment is a common bottleneck in various macromolecular delivery approaches. Recently, the polycationic peptide dfTAT was identified as a reagent that induces the efficient leakage of late endosomes and, thereby, enhances the penetration of macromolecules into the cytosol of live human...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioconjug Chem
Hauptverfasser: Najjar, Kristina, Erazo-Oliveras, Alfredo, Mosior, John W., Whitlock, Megan J., Rostane, Ikram, Cinclair, Joseph M., Pellois, Jean-Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905407/
https://ncbi.nlm.nih.gov/pubmed/29065262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00560
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