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Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment

Arginine-rich cell-penetrating peptides (AR-CPPs) are very promising tools for the delivery of therapeutic macromolecules such as peptides, proteins, and nucleic acids. These peptides allow efficient internalization of the linked cargos intracellularly through the endocytic pathway. However, when li...

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Autors principals: El-Sayed, Ayman, Futaki, Shiroh, Harashima, Hideyoshi
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664872/
https://ncbi.nlm.nih.gov/pubmed/19125334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9071-2
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