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Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment

Arginine-rich cell-penetrating peptides (AR-CPPs) are very promising tools for the delivery of therapeutic macromolecules such as peptides, proteins, and nucleic acids. These peptides allow efficient internalization of the linked cargos intracellularly through the endocytic pathway. However, when li...

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Detalhes bibliográficos
Main Authors: El-Sayed, Ayman, Futaki, Shiroh, Harashima, Hideyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664872/
https://ncbi.nlm.nih.gov/pubmed/19125334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9071-2
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