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Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment

Arginine-rich cell-penetrating peptides (AR-CPPs) are very promising tools for the delivery of therapeutic macromolecules such as peptides, proteins, and nucleic acids. These peptides allow efficient internalization of the linked cargos intracellularly through the endocytic pathway. However, when li...

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Bibliographic Details
Main Authors: El-Sayed, Ayman, Futaki, Shiroh, Harashima, Hideyoshi
Format: Artigo
Language:Inglês
Published: Springer US 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664872/
https://ncbi.nlm.nih.gov/pubmed/19125334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9071-2
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